For example, we now know that a common enzyme called "DNase I" does not degrade switchback DNA as quickly as it degrades conventional B-DNA (the DNA that is generally found in living organisms).

These so-called normal or reverse Hoogsteen interactions allow a third strand to join and form a beautiful triple helical structure: a triplex (figure 2). In the new article published in the ...

Jun 16, 2023: Revolutionary new method can manipulate the shape and packing of DNA (Nanowerk News) A human cell harbors roughly 2 meters of DNA, encompassing the essential genetic information of an ...

Chromosomes have a thinner junction point called a centromere and at their ends are protected by repetitive sequences of DNA called telomeres. In humans, chromosomes remain in separate territories ...

Researchers have developed a revolutionary new method, called triplex origami, to manipulate the shape and tight packing of DNA. The new discoveries open up exciting new possibilities in gene therapy, ...