BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

A novel method for the synthesis of N-linked glycopeptides using the sugar-assisted ligation strategy from cysteine free peptides is presented. The ligation junction tolerates a variety of amino acids ...

Summit Health Announces Internalization of Genomic Testing Cooperative State-of-The-Art Next Generation Sequencing DNA and RNA Profiling Tests ...

PacBio enhances methylation detection in HiFi sequencing by licensing advanced methods, improving insights into DNA modifications.

Gordon Sanghera, PhD, co-founder and CEO of Oxford Nanopore Technologies, holds one of his company’s MinION palm sized native DNA/ RNA sequencers in a 2023 video interview with the British ...

A new study shows that long-read sequencing has the potential to improve the rate of diagnosis while reducing the time to diagnosis from years to days — in a single test and at a much lower cost.

The cause of rare diseases is increasingly being detected through genome sequencing, which involves reading the entire human DNA by first breaking it into small pieces—short reads. Christian ...

In this work, we employ direct RNA sequencing with nanopores, enhanced by 5ʹ end adapter ligation, to comprehensively interrogate the human transcriptome at single-molecule and -nucleotide resolution.

Trinity is the first major advancement in exome target capture sequencing in over two decades, streamlining a traditionally complex, hands-on process to capture and sequence key regions of DNA.

The autosomal dominant cancer predisposition disorders hereditary breast and ovarian cancer (HBOC) and Lynch syndrome (LS) are genetic conditions for which early identification and intervention have a ...