Beneath the surface of present-day western Honduras lie the ruins of Copán—an archaeological site that once stood as a vital ...

A protein called PriC allows DNA replication to proceed in Escherichia coli when the complex that usually initiates this process is compromised.

Additionally, the scientists unexpectedly captured for the first time a detailed picture of how the "engine" driving the cellular replication machinery moves along DNA in human cells. Their ...

By knocking out TEFM, they observed a notable reduction in mtDNA copy number, alongside a decrease in 7S DNA levels and strand-asynchronous replication intermediates. These findings suggest that TEFM ...

With only seven genes, the BK polyomavirus must use the host cell’s DNA replication machinery to ... The prevailing model suggests that BKPyV expresses a protein called large tumor antigen ...

To better understand BKPyV replication ... model suggests that BKPyV expresses a protein called large tumor antigen, or TAg, early during infection. Early expression of TAg was thought to push kidney ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind ...

If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their ...

The findings visualize for the first time a molecular complex -- called CTF18-RFC in humans and Ctf18-RFC in yeast -- that loads a 'clamp' onto DNA to keep parts of the replication machinery from ...

Much as ChatGPT generates poetry, a new A.I. system devises blueprints for microscopic mechanisms that can edit your DNA. The physical ... driven by a similar A.I. model that learns from sequences ...

Brandt Eichman and Walter Chazin, professors of biochemistry, have worked together to provide a better understanding of how exactly DNA replication ... A mechanistic model of primer synthesis ...