The reconstructed vesicle cycle model provides critical insights into synaptic transmission, advancing neuroscience and ...

Firstly, we construct a small-scale network with neurons interconnected by electrical synapses in addition to chemical synapses. Basic properties of this small-scale neural network in processing ...

How do we think, feel, remember, or move? It all depends on transmission of chemical signals in the brain, carried and released by molecular containers called vesicles. In a new study, researchers ...

CPGs. Their model shows that cell-type-specific connectivity and a dominant inhibitory drive could underlie rhythm generation. Excitatory input could act to enhance the frequency range of these ...

Once triggered by norepinephrine, astrocytes produced a second chemical that they released onto synapses, which caused the dampening of synapse activity. Even when neurons' ability to directly ...

Researchers at the University of São Paulo (USP) in Brazil have succeeded in showing, in an animal model, that the process of insulin resistance in the brain affects both Alzheimer's disease and ...

In this work, we introduce RGBChem, a novel approach for converting chemical compounds into image representations ... (17) They used the SMILES representation and applied a one-hot encoding technique ...

MolR uses graph neural networks (GNNs) as the molecule encoder, and preserves the equivalence of molecules w.r.t. chemical reactions in the embedding space. Specifically, MolR forces the sum of the ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

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