Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. (Nanowerk News) ...

This study is the first to show that the host can selectively target specific microbes by recognizing their unique lipid signatures. Interestingly, unlike typical antimicrobial proteins that kill ...

Phase III trial data support obicetrapib's lipid controlling effects in high-risk individuals without sufficient response to other lipid-lowering therapies. Obicetrapib is a highly selective CETP ...

A schematic illustration of the role of DHHC5 and CRYBG1 in controlling lacteal function and intestinal lipid absorption by maintaining the lipid raft association of VEGFR2. The proper functioning ...

Two agents targeting angiopoietin-like protein 3 safely lowered lipid levels in phase 2 trials. Solbinsiran and SHR-1918 will be further studied in patients with high lipid levels in phase 3 trials.

The relationship between variability in lipid fractions and the risk for heart failure remains understudied, particularly in patients with T2D who are at an increased risk for both dyslipidemia ...

Lipid nanoparticles (LNPs) play a critical role for mRNA therapies because they protect the nucleic acid material from degradation as it is delivered to the targeted cell. Precise characterization ...

Now, scientists led by Christiane Ruedl of Nanyang Technological University, Singapore, report that blocking lipid buildup in these cells restores their capacity to engulf Aβ, leading to fewer plaques ...

LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...

The word “lipid” is another word for “fat.” Lipids can be both solid or liquid at room temperature, in which case they are called fats or oils, respectively. For several decades ...

Now a new study published in Gut offers what might be a crucial insight: specific lipids, or fatty acids, that are abundantly found in ultra-processed foods may be promoting inflammation that ...

Lipid nanoparticle mRNA vaccine, 3D illustration. [Dr_Microbe/Getty Images] To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used ...