The 49ers travel to New Orleans for the first time since the 2020 season and look to earn their first win at Caesars Superdome since their 48-46 victory against the Saints in 2019. San Francisco owns ...

San Francisco is 18-27 all-time against Indianapolis, including a 7-15 mark on the road. The Niners will face the Colts in prime time for the second time in franchise history and the first since ...

The Indianapolis Colts have their 2025 ... Kansas City Chiefs, and San Francisco 49ers will be tough. Also, the Colts have two meetings with the reigning AFC South champion Texans, against which ...

That's what many people think about the Indianapolis ... as the Colts have one primetime game scheduled-- Week 16 at Lucas Oil Stadium against the San Francisco 49ers on Monday Night Football ...

If the San Francisco 49ers are going to rebound from a last ... Tennessee Titans, 1:25 p.m. WEEK 16 - at Indianapolis Colts, 5:15 p.m. (Monday Night Football) WEEK 17 - vs. Chicago Bears, 5: ...

The Indianapolis Colts will learn their 2025 schedule ... Arizona Cardinals, San Francisco 49ers, Miami Dolphins, Atlanta Falcons. Road games: Kansas City Chiefs, Los Angeles Chargers ...

Indianapolis has initially been given just one primetime game in 2025, an appearance on ESPN's "Monday Night Football," a Dec. 22 tilt against the San Francisco 49ers. Colts owner Jim Irsay has ...

Home: Arizona Cardinals, San Francisco 49ers, Seattle Seahawks, Houston Texans, Indianapolis Colts, New Orleans Saints, Tampa Bay Buccaneers, Detroit Lions Away: Arizona Cardinals, San Francisco ...

Now that we know what the Indianapolis Colts' 2025 schedule looks like ... while finding some home victories against the San Francisco 49ers, Atlanta Falcons, Cardinals, Broncos and Raiders.

Indianapolis Colts ... whom the Colts went 1-3 against last year, with tough matchups against the Seattle Seahawks and San Francisco 49ers wedged in between. The toughest game of this end-of ...