Here, we found that the interaction between the v-SNARE protein VAMP3 on TfR vesicles and the t-SNARE protein syntaxin 4 that is limited to the basolateral membrane in HBMECs mediates the fusion. We ...

Uncertainty is a crucial aspect in real-life scenarios, especially when dealing with ambiguous information from multimodal data sources. Complex evidence theory (CET), a generalized form of ...

Endocytosis has been the bane of the intracellular delivery efficiency of nanoscale systems. A class of delivery systems, viz., cell membrane-coated nanoparticles (CMNPs), show efficacious and even ...

Further experiments revealed that a dedicated soluble-N-ethylmaleimide-sensitive-factor attachment protein receptor (SNARE) complex, a group of membrane-bound proteins that mediate vesicle fusion ...

Vaccinex's proprietary ActivMAb ® Technology enables expression of functional, properly folded complex proteins such as GPCRs and ion channels on the relatively simple membrane of poxvirus ...

With over 15 years of experience in antibody discovery and functional characterization, Riley brings specialized expertise in the study of complex membrane proteins, including ion channels, G ...

If researchers know more about how chlamydia membrane fusion works, they could one day harness those mechanisms to fight infections that no longer respond to antibiotics.

Hines has submitted plans to build a 220K square foot R&D complex for startup Pacific Fusion at Alameda Point, the waterfront site of the former Naval Air Station Alameda.

More information: Chanwoo Lee et al, Exocyst stimulates multiple steps of exocytic SNARE complex assembly and vesicle fusion, Nature Structural & Molecular Biology (2024).

Single-molecule localization imaging shows that the Nipah virus fusion protein forms nanoscale clusters on cell and viral membranes that favor membrane fusion activation.