Scientists at the Broad Institute of MIT and Harvard have identified 4,208 previously unannotated open reading frames (ORFs) across 679 human-associated viral genomes using a high-throughput method ...

New study shows RNA polymerase I halts at abasic DNA damage, helping prevent faulty rRNA production and exposing lesions for ...

Massively Parallel Ribosome Profiling (MPRP) enables rapid identification of viral proteins without the need to grow live ...

For a long time, scientists depended on luck to find new proteins. In 1840, for example, Friedrich Ludwig Hünefeld, a German ...

In “Let-7a-regulated translational readthrough of mammalian AGO1 generates a microRNA pathway inhibitor” by Singh et al, 2019, and “Transcript-specific induction of stop codon readthrough using a ...

The ribosome consists of two ribonucleoprotein subunits. The small subunit mediates the interactions between the anticodons of the tRNAs and the codons in the mRNA that they are translating to ...

In many genetic diseases, a small error in the DNA code can have devastating effects. These errors, called nonsense mutations ...

Northwestern Medicine scientists have uncovered new details about how poxvirus hijacks its host's protein synthesis machinery to multiply and spread, according to a study published in Nature ...

A paradigm shift in the way we treat spinal injuries is now in sight, with the world's first regenerative cell therapy being granted approval for a registrational Phase I clinical trial.

Cells rely on ribosomes to translate genetic messages into proteins, a job that underpins everything from metabolism to growth. Researchers have long believed that when ribosomes encounter an obstacle ...

Key Laboratory of Cluster Science Ministry of Education, Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion Materials, Advanced Technology Research ...