Looking at life today, it is difficult to imagine how complex biological processes and structures could have developed from ...

Based on several lines of interesting data, the authors conclude that FMRP, though associated with stalled ribosomes, does not determine the position on the mRNAs at which ribosomes stall. Although ...

The ribosome, through well-choreographed processes, translates genetically encoded messages on mRNAs to polypeptides. While structural and biochemical studies of prokaryotic 70S ribosome have enhanced ...

Ricin is a ribosome inactivating protein that catalytically removes a universally conserved adenine from the α-sarcin/ricin loop (SRL) of the 28S rRNA. We recently showed that ricin A chain (RTA) ...

In response to diverse stress stimuli, eukaryotic cells activate a common adaptive pathway, termed the integrated stress response (ISR), to restore cellular homeostasis.The core event in this pathway ...

Massively Parallel Ribosome Profiling (MPRP) enables rapid identification of viral proteins without the need to grow live viruses. genprowebdirectory Facebook Linkedin RSS Twitter Youtube ...

Ribosomes have been the focus of structural and biochemical studies for more than 50 years. Recently, high-resolution structures have provided molecular snapshots of different intermediates in ...

Poxvirus alters host ribosome function to prioritize viral protein synthesis, inducing structural changes in the 40S subunit and utilizing factors such as RACK1 and eIF3.

A new variant of COVID-19 is circulating in parts of the world and may be driving an increase in cases in the eastern Mediterranean, Southeast Asia and western Pacific regions.