Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older. The ...

Transposon said its oral small molecule TPN-101 has been selected for testing as part of the HEALEY ALS platform trial.

Prime editing is an advanced gene editing technology that enables precise DNA corrections without introducing double-stranded breaks, significantly reducing off-target effects. This innovation holds ...

A UVa researcher has discovered that NRTIs, drugs used to treat HIV, can also help prevent Alzheimer's and a long list of ...

A new UVA study finds that HIV drugs like NRTIs may reduce Alzheimer's risk by 10% annually, suggesting potential for ...

Exposure to nucleoside reverse transcriptase inhibitors (NRTIs), which treat HIV and hepatitis B and inhibit inflammasome activation, is associated with a significantly lower incidence of Alzheimer ...

We report the first use of human telomerase reverse transcriptase (hTERT) expression in experimental xenotransplantation. Previously, we showed that bovine adrenocortical cells can be transplanted ...

NRTI = nucleoside reverse transcriptase inhibitor, NNRTI = nonnucleoside reverse transcriptase inhibitor, PI = protease inhibitor. b While this has not been reflected in the IAS-USA and BHIVA ...

More information: Kaiyang Zheng et al, Diversity of reverse-transcriptase-containing viruses through global metagenomics, ...

If you're getting treated for an HIV infection, your doctor may suggest a type of drug called an NRTI. It's short for "nucleoside/nucleotide reverse transcriptase ...

Amid the unprecedented challenges presented by the COVID-19 pandemic, a once obscure enzyme found itself in the spotlight: reverse transcriptase. As laboratories worldwide rushed to develop ...

Summary: While single mutations confer resistance to earlier nonnucleoside reverse transcriptase inhibitors (NNRTIs), etravirine exhibited an increased barrier to resistance by requiring multiple ...