To optimize the retroviral vector design for hematopoietic stem cell gene therapy of MPS type I, we have constructed 10 retroviral vectors to evaluate the effects of selectable markers, promoter ...

Retroviral vector sequence maps commonly show the vector incorporated into a plasmid including full LTRs as cloned.

Gilead uses the Oceanside facility for commercial retroviral vector production and clinical manufacturing as well as process development of its biologics candidates.

These findings suggested that active retroviruses and retrovirus-derived retroelements evolved differential expression patterns in ovarian tissues, with retroviruses being active in somatic cells and ...