In previous clinical trials involving children with X-linked severe combined immunodeficiency (SCID-X1), a Moloney murine leukemia virus–based γ-retrovirus vector expressing interleukin-2 ...

We generated retrovirus-producing Mφ by transducing the WGL5 cells with a replication-defective retroviral vector carrying the enhanced green fluorescent protein (EGFP) reporter gene and the ...

Retroviral vectors that are both non-replicating and non-integrating represent a novel and attractive tool that has potential advantages for gene delivery therapy, immunotherapy, and vaccinology ...

This article examines viral and non-viral vectors in gene therapy, highlighting their mechanisms, advantages, and limitations ...

A retrovirus is a virus that uses its own RNA to replicate inside healthy cells. Learn what the causes and symptoms of retroviruses are along with the treatment options available.

The Vector Development Laboratory provides comprehensive service in the design, creation, production, and analysis of standard gene therapy. To help investigators chose the optimum vector system for ...

Charles River Laboratories International, Inc. CRL and Captain T Cell, a spinoff from Max Delbrück Center in Germany, entered into an agreement on plasmid DNA and retrovirus vector production ...

New research into how a retrovirus is spreading across populations of wild koalas in Queensland, Australia is leading to a better understanding of the evolution of the animal's genome.

There are several types of viral vectors that can be used to deliver nucleic acids into the genetic makeup of cells, including retrovirus, lentivirus, adenovirus, adeno-associated virus and herpes ...

Using Cygnus’s BSL-1 compatible viral clearance kits, you can easily and economically quantify viral clearance for downstream process steps right in your own lab and on your timeline.

Retroviral vectors that are both non-replicating and non-integrating represent a novel and attractive tool that has potential advantages for gene delivery therapy, immunotherapy, and vaccinology.

Retroviral vectors that are both non-replicating and non-integrating represent a novel and attractive tool that has potential advantages for gene delivery therapy, immunotherapy, and vaccinology ...