Here, authors present apical-out nasal organoids using a biochemically defined hydrogel system, revealing that matrix metalloproteinases are required for normal epithelial development.

Since this work targets the immune system and not the specific virus, the models are expected to impact many respiratory infections, including COVID-19 "The immune system is a complex, interactive ...

The respiratory system is responsible for the exchange of carbon dioxide and oxygen in the human body. This system also helps remove metabolic waste products and keep pH levels in check.

The researchers incorporated this understanding of the impact of environmental factors on droplet spread into a new mathematical model that can be used to predict the early spread of respiratory ...

Thirteen factors were identified as potential predictors of acute respiratory distress syndrome. With these factors, the model had positive predictive and discriminatory ability in sepsis patients.