A major problem in solid-phase peptide synthesis (SPPS) is aggregation and poor solvation leading to incomplete deprotection and/or coupling steps, resulting in low crude purity peptides.

The Peptide Builder accommodates a wide range of synthesis scales, from 50 µmol to 1.0 mmol. It can be used with any kind of polymeric resin, including PS, PEGylated resins, and the standard ...

Solid Phase Peptide Synthesis (SPPS) method is carried out on solid support called as resin. The specific characters of peptide like high specificity, high bioactivity, and low toxicity has made ...

demonstrating fully automated solid phase peptide synthesis. The process begins with swelling Tentagel S resin in DMF, preheating and Fmoc deprotection using 20% Piperidine in DMF. A reduction in ...

ChemMatrix is a patented 100% PEG resin from Matrix Innovation® that offers substantial advantages over traditional PS and PEG based resins for solid phase peptide synthesis. “Biotage is a leader in ...

Peptide synthesis is a huge market in the pharmaceutical ... A filter in the vessel will retain the resin (with the peptide attached) while allowing solutions to be drained out.

peptide synthesis in an aqueous environment, syntheses of glycosylated peptides and viral peptides, and on-resin ring closing metathesis. There was also a poster discussing the synthesis of a 111-mer ...