Diabetic kidney disease (DKD) imposes a heavy medical burden worldwide due to the lack of effective treatment. High levels of mtROS and mitochondrial damage in the renal tubules are the initiating and ...

Type IV renal tubular acidosis is important cause of generally mild hyperkalemia, and it is a treatable condition. ''Polypharmacy'' -which is very common in diabetic patients due to accompanying other ...

These renal manifestations may predate the onset of sicca symptoms. Hypokalaemia can be caused by distal renal tubular acidosis and, in rare cases, can be severe enough to produce hypokalaemic ...

We have recently had the opportunity to study a boy with hypercalcemic nephropathy in whom renal tubular acidosis and renal potassium wasting apparently developed as a result of repeated episodes ...

Renal Tubular Acidosis (RTA) is a complex kidney disorder that disrupts the body's acid-base balance, leading to a range of ...

Renal tubular acidosis may signal subclinical kidney involvement in patients with mutations in the TTR gene, according to new research.

THE syndrome of renal tubular acidosis is a clinical disorder resulting from impaired renal tubular control of acid–base metabolism. Since first described by Lightwood1 in 1936, cases have been ...

It also presents extraglandular manifestations. The main renal manifestation is tubulointerstitial nephritis (TIN), which can manifest as renal tubular acidosis (RTA). Urinary citrate may be a ...

Less frequently, patients might present with tubulointerstitial disease manifested as renal tubular acidosis or isolated interstitial nephritis. Hypertension is common and can be severe.

ADV7103 was also granted an ODD status by the FDA in 2022 for the treatment of patients with distal renal tubular acidosis (dRTA). 2 According to Advicenne, ADV7103 is a combination of potassium ...