Researchers at Texas Biomedical Research Institute and the University of Chicago have uncovered a mechanism that SARS-CoV-2, ...

A new study found that aged neurons have defects in key proteins that make them vulnerable to molecular stress and neurodegenerative damage.

As the global population ages, the risk of developing neurodegenerative diseases such as dementia, Alzheimer's disease, ...

Unnecessary sequences called 'introns' are removed from gene transcripts. But where do they come from? | Genetics And ...

A new study has revealed a set of proteins in the cerebrospinal fluid that could help identify frontotemporal dementia (FTD) ...

RBPs (RNA-binding proteins) perform indispensable functions ... advance basic and translational cardiovascular research. Alternative pre-mRNA splicing is a fundamental mechanism of ...

Scientists are interested in this as a way to further understand genome evolution, but also because introns allow for a crucial process called “alternative splicing.” Introns must be spliced out of ...

The authors review methodologies to detect post-transcriptional splicing, the mechanisms controlling splicing ... advances have enabled discoveries of RNA polymerase interactions with RNA ...

The present study aimed to explore the dysfunctional mechanism of cellular senescence in AD by joint analysis of single-cell RNA (scRNA) and bulk sequencing data to identify the key transcription ...

“This groundbreaking discovery of a novel RNA-targeted mechanism to restore functional protein for FXS and the feasibility of a biomarker to detect mis-splicing of FMR1 in FXS patients opens up a ...

Surprisingly, this shift did not significantly change global gene activity, but it altered how certain RNA transcripts were processed—a mechanism known as alternative splicing, which enables ...