The authors review methodologies to detect post-transcriptional splicing, the mechanisms controlling splicing ... advances have enabled discoveries of RNA polymerase interactions with RNA ...

RNA splicing is a modification of the nascent ... and explore its impacts and mechanisms in the nematode nervous system. Profiling alternative splicing in single cells is challenging due to ...

Surprisingly, this shift did not significantly change global gene activity, but it altered how certain RNA transcripts were processed—a mechanism known as alternative splicing, which enables ...

The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology. As critical regulators of gene expression ...

A new study found that aged neurons have defects in key proteins that make them vulnerable to molecular stress and neurodegenerative damage.

Unnecessary sequences called 'introns' are removed from gene transcripts. But where do they come from? | Genetics And ...

As the global population ages, the risk of developing neurodegenerative diseases such as dementia, Alzheimer's disease, ...

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

Advancements in gene therapy for Duchenne muscular dystrophy (DMD) have improved the outlook for some patients, but further ...

Discover how neurodegenerative diseases may start with blood-brain barrier damage, leading to memory loss and cognitive decline.