In conclusion, in-cell SHAPE-MaP enables RNA structure to be examined at single-nucleotide resolution in a native cellular environment, including for RNAs of low to moderate abundance. In-cell ...

SCOPER has simplified it significantly. Say you want to study a new RNA: First, put the nucleotide sequence into one of the open-source, AI-based structure prediction tools available today.

"It's relatively easy to discover the nucleotide sequence of an RNA molecule ... having to compare different possible predictions of RNA structure, the scoring function provides a measure of ...

Researchers at Ruhr-Universität Bochum (RUB) describe a way to use AI to reliably predict the structure of certain RNA molecules from their nucleotide sequence in the journal PLOS Computational ...

"It's relatively easy to discover the nucleotide sequence of an RNA molecule ... having to compare different possible predictions of RNA structure, the scoring function provides a measure of ...

Its twisted, double-helix structure is one of the most ... an incredibly important role in forming DNA and RNA strands by linking each nucleotide to the next. If you imagine a strand of nucleic ...

Inspired by historical work showing that structure plays a role in the function ... decided to investigate which regions of the 600-nucleotide RNA molecule are crucial to its function.

Pseudouridine is an isomer of uracil, meaning it has the same chemical formula but a different structure. It is often referred to as the "fifth nucleotide" due to its abundance in RNA. Pseudouridine ...