Candida auris is a dangerous fungal pathogen that has become a global health concern. It spreads easily in health care settings and can cause life-threatening infections, especially in patients with ...

A study published in mBio details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the "macrodomain," found in all coronaviruses such as SARS-CoV-2 and ...

The DHODH inhibitor market is poised for steady growth, fueled by the rising burden of autoimmune and inflammatory diseases, along with incre ...

Pyrimidine compounds acting as ubiquitin carboxyl-terminal hydrolase 1 (USP1) inhibitors and reported to be useful for the treatment of cancer have been disclosed in a recent Asieris Pharmaceuticals ...

After F2G’s first attempt to get a brand-new class of antifungal to market was derailed by the FDA, the U.K.-based biotech has secured $100 million in fresh funding to bankroll another push ...

Garg, S., Kumar, R., Kunimoto, D. and Rayat, G.R. (2022) Anti-Mycobacterial Activity of Flavonoid and Pyrimidine Compounds. Molecules, 27, Article 6714.

Reactions have been discovered that selectively transform nitrogen-containing rings, called pyrimidines, into various other ring systems — enabling rapid preparation of compound libraries for ...

RAPT Therapeutics has been granted a patent for pyrazole pyrimidine compounds that target hematopoietic progenitor kinase 1. The compounds can be used for therapeutic purposes. GlobalData’s report on ...

Shanghai Visonpharma Co. Ltd. has identified pyridine [4,3-d]pyrimidine compounds acting as Toll-Like receptor 7 (TLR7) and TLR8 agonists reported to be useful for the treatment of cancer and viral ...

Nitrogen is a vital component of life and human culture. But today, the majority of the N atoms in synthetic N-containing compounds come from NH3, which is mass-produced using the Haber-Bosch method, ...