Here we describe the total chemical synthesis ... N-terminal cysteine sulfhydryl side chain. A subsequent, rapid, intramolecular rearrangement yields a native peptide bond at the site of ligation (3, ...

DsRed and its mutants were purified as described (5) by using the N-terminal polyhistidine ... was found to create large protein aggregates. To test for light sensitivity of protein maturation, the ...

Scientists observe ribosomal cooperation that prevents pauses in protein synthesis, revealing new dynamics for cellular ...

Northwestern Medicine scientists have uncovered new details about how poxvirus hijacks its host's protein synthesis machinery ...

The conventional view of memory consolidation predicts that blockade of protein synthesis should block new ... but rats still received an infusion of vehicle (n = 6) or the high dose of anisomycin ...

rather than skewing it towards dinner “stimulated 24-hour muscle protein synthesis more effectively,” according to researchers at the University of Texas Medical Branch. The body benefits ...

Compared with enzymes, protein catalysts are simpler, more stable at high temperatures, and can also be used in environmentally friendly organic solvents like ethanol, allowing chemists to load up ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

The FDA also approved the VENTANA MET (SP44) RxDx Assay (Roche Diagnostics) as a companion diagnostic to detect high c-Met protein overexpression, defined as 50% or more of tumor cells with 3 ...

The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...

in which no increase in protein synthesis, ribosome formation or DNA synthesis has been found after treatment with silymarin. [44] The therapeutic activity of silymarin against mushroom poisoning ...