Protein Coupled Receptor (GPCR) Targeting: Technologies and Global Markets" is expected to grow from $4.4 billion in 2024 to $6.1 billion by the end of 2029, at a compound annual growth rate (CAGR) of ...

A protein-engineering strategy, in which a constitutively active form of an immune receptor is kept inactive by a peptide ...

Taste, pain, or response to stress — nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers at the ...

The GRAFS classification system of G-protein coupled receptors in comparative perspective. Gen Comp Endocrinol. 2005;142(1):94-101. Rosenbaum DM, et al. The structure and function of G-protein-coupled ...

Viruses and bacteria are always trying to sneak into our bodies, but researchers at the University of Missouri are discovering that our own biology may already hold the keys to fighting off some of ...

Wikimedia Commons, Valeryns The 2012 Nobel Prize for Chemistry goes to Robert J. Lefkowitz of Duke University and Brian K. Kobilka of Stanford University for their work in discovering the inner ...

This important study fills an gap in our knowledge of the evolution of GPCRs in holozoans, as well as the phylogeny of associated signaling pathway components such as G proteins, GRKs, and RIC8 ...

Molecular glues, tiny molecules that connect one protein to another, are promising targets for pharmaceutical research. By linking a disease-related protein to one that triggers a cell's demolition ...

The scientists used cryo-EM techniques, which allow the three-dimensional architecture of proteins to be seen in great detail. In the current study, cryo-EM revealed the structure of TAS2R14 ...

Within cell membranes, ion channel receptors typically activate in response to electrical, chemical or other specific stimuli, explains Feng Qin, PhD, professor of physiology and biophysics and senior ...