Mitogen-activated protein kinase (MAPK) is an integral component ... To investigate the role of the MAPK cascade in mammalian learning, we determined if learning is associated with activation ...

Following activation, Met signaling is elicited via its interactions with SH2-containing proteins ... Met-induced activation of another MAP kinase cascade, the ERK pathway, in a Crk-independent ...

Scientists have found that lemborexant not only increased restorative sleep in male mice but also reduced levels of toxic tau ...

Semaglutide, a synthetic analog of glucagon-like peptide-1 (GLP-1), has garnered attention for its intriguing properties and potential implications in various r ...

Abstract:        Obesity, a growing global issue, has been closely associated with an increased risk of various cancers, especially breast cancer. El ...

Biodexa Announces Recruitment of First Patient in Phase 2 Study of Tolimidone in Type 1 Diabetes ...

SNF1-related protein kinase 2s (SnRK2s ... stress tolerance and ABA responses as well as in growth and development. Our findings uncover a kinase cascade mediating osmoregulation in higher plants.

An international research team led by Professor Manuel Maestre-Reyna from National Taiwan University has filmed a high-resolution, 3D molecular movie of a cryptochrome in action. The work is published ...

This study presents compelling evidence that the denitrosylase SCoR2 regulates cardioprotective metabolic reprogramming in the heart following ischemia/reperfusion injury. The findings are supported ...

The unfolded protein response (UPR) is a crucial signaling network that preserves endoplasmic reticulum (ER) homeostasis, impacting both health and disease. When ER stress occurs, often due to an ...

The AMP-activated protein kinase (AMPK) system acts as a sensor of cellular energy status that is conserved in all eukaryotic cells. It is activated by increases in the cellular AMP:ATP ratio caused ...