New method developed by UTSW researchers removes mysterious organelles from stem cells and embryos to uncover their roles.

Google's DeepMind launches AlphaGenome, an artificial intelligence model that predicts gene expression from DNA sequence.

Scientists identified 473 human genes that act as genetic “on/off switches,” shaping disease risk through tissue-specific or universal patterns regulated by DNA changes and hormones. These ...

Understanding human biology requires more than mapping our genes—we must also understand how gene expression is regulated to guide healthy development, growth, and maintenance of our body ...

This cooperative binding hints that gene regulation isn’t just a straightforward reading of a DNA blueprint by lone architects. Instead, it’s more like a bustling construction site where multiple ...

The personalized CRISPR treatment could be the future of gene therapy, but hurdles remain before everyone has access.

In this editorial, the authors describe the foundations of an N-of-1 gene-editing study to treat an infant with a urea-cycle disorder.

Base editors can correct disease-causing genetic variants. After a neonate had received a diagnosis of severe carbamoyl-phosphate synthetase 1 deficiency, a disease with an estimated 50% mortality ...

Researchers use generative AI to design synthetic enhancers that can effectively control gene expression in healthy mammalian cells.

Cells are constantly on the move, whether in a developing embryo or metastatic cancer. But how do cells adapt to the new environments they encounter? Traditionally, scientists have believed that cells ...

The parasite that causes malaria requires precise control of gene expression to progress through the various stages of its complex life cycle. A new study, by a multinational team of researchers ...

This study provides a vital mechanism proving that IPMK, a key enzyme in the inositol metabolism system, is a major transcriptional activator in the core gene expression network of animal cells.