Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

This study presents a valuable advance for the analysis of gene expression variation at the level of individual cells by introducing a novel reference-free framework that can detect splicing, fusion, ...

Unraveling the Complexities, Risks, and Latest Breakthroughs in Diagnosis and Treatment Introduction to Coxsackievirus: Classification and Virology Epidemiology and Global Distribution Patterns ...

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not ...

Chemists have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth -- a key process in the origin of life.

Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have ...

Transposable elements contribute to evolution, but their own diversification remains incompletely understood. Here, insect ...

Northwestern Medicine investigators have discovered that a novel long noncoding RNA (lncRNA), which are usually 200 ...

Currently, the researchers are using CRISPR-TO to move endogenous RNAs – RNA molecules that are naturally produced within the ...

In a new study published in Cell Genomics, researchers use RNA sequencing to characterize bone metastases from eight cancer types. The findings ...