Researchers outline their improved lipid-polymer nanoparticle for holding mRNA that is stable when nebulized and successfully delivers aerosols (liquid droplets) into mice's lungs.

The global lipid nanoparticles (LNP) contract development and manufacturing organization (CDMO) market is poised for ...

Researchers outline their improved lipid-polymer nanoparticle for holding mRNA that is stable when nebulized and successfully delivers aerosols (liquid droplets) in mice’s lungs. An improved lipid ...

Insight into the Mechanisms Driving the Self-Assembly of Functional Interfaces: Moving from Lipids to Charged Amphiphilic Oligomers. Journal of the American Chemical Society , 2019; 142 (1): 290 ...

Modified polymer could help people with PEG allergies Tweaking the polyethylene glycol layer around lipid nanoparticles could prevent rare reactions to drugs, including some COVID-19 vaccines ...

Polymerization of 1,2-bis(tricosa-10,12-dinoyl)-sn-glycero-3-phosphocholine, DC8.9PC, which is a photo-polymerizable lipid, has been systematically investigated in various biological membrane ...

Polymer nanoparticles may be the answer. With virtually unlimited options for chemical features, “you can design bespoke delivery vehicles easier than with a lipid-based system,” says Sean ...

Morphology and Physical Properties of Hydrophilic-Polymer-Modified Lipids in Supported Lipid Bilayers, Langmuir, 34(24), 7201-7209. 10.1021/acs.langmuir.8b00870 Journal Langmuir ...

Soluble polymer fibres: The slime of velvet worms contains nanoglobules made up of lipids and proteins. Shear forces cause the proteins to form fibres covered by a fatty layer. The fibres can ...

Zwitterionic Polymer-Functionalized Lipid Nanoparticles for the Nebulized Delivery of mRNA. Journal of the American Chemical Society , 2024; DOI: 10.1021/jacs.4c11347 Cite This Page : ...

A study in the Journal of the American Chemical Society reports steps toward making inhalable mRNA medicines a possibility. Researchers outline their improved lipid-polymer nanoparticle for ...