Of the five species of Plasmodium that cause malaria ... in trials in malaria-endemic regions target the P. falciparum sporozoite—the life stage of the parasite that is transmitted from ...

The majority of cases occur in Africa, where Plasmodium falciparum is the most prevalent and children account for most deaths. Efforts to combat malaria include vaccines and monoclonal antibodies ...

A recent study has identified a previously unknown antibody target on the Plasmodium falciparum sporozoite surface, providing ...

Preventing blood coagulation is important for mosquito nutrition, but keeping blood soluble can aid Plasmodium parasites’ survival ... where they merge and develop into infectious cells called ...

Scientists have discovered a new type of anti-malarial antibody that doesn't interfere with current vaccines, at least in mouse models. Could they help eliminate malaria in the future?

"The discovery of a new target on the sporozoite surface [the life stage ... shown to be safe and efficacious against infection with Plasmodium falciparum, which is the deadliest malaria-causing ...

The sporogonic cycle of Plasmodium vivax was established and maintained under ... however the Tecojate strain developed higher sporozoite loads. Intravenous inoculation of Aotus monkeys with ...

and produce partial protection manifest as delayed parasitemia after sporozoite challenge with a different strain of Plasmodium falciparum. Such heterologous prime-boost immunization approaches ...

the mAbs prevent sporozoites from infecting the liver, where they otherwise develop into blood-stage parasites that infect blood cells and cause disease and death. Plasmodium falciparum sporozoites ...