In the second part of his Pharma Commerce video interview, Hyung Heon Kim, CEO of MetaVia, explains how dual-action metabolic therapies can address clinical or tolerability gaps observed in ...

Partial agonists are a subclass of beta blockers used to treat hypertension in many countries. Partial agonist act by stimulating beta receptors when they are quiescent and blocking beta receptors ...

Applying molecular modeling based on active state MOR structures and synthesis of novel ligands and using newer assays with limited receptor reserve, the opioid field is revisiting the strategy of ...

As patients increasingly turn to cannabis for chronic pain, clinicians grapple with mixed evidence and a lack of high-quality ...

We sought studies that examined the blood pressure-lowering effects of treatment with six beta-blockers with partial agonist activity at different times throughout a 24-hour period, measured by a ...

Although D3R partial agonists and antagonists have been shown to influence cocaine seeking in rodents, effects have been inconsistent with studies reporting varying outcomes on cocaine-associated ...