Primary care physicians play a vital role in identifying red flags for rare eosinophilic diseases like HES and EGPA, enabling ...

The Lancet on the anti-IL-5 antibody mepolizumab in individuals with allergic asthma, evidence has accumulated that the pathogenetic role of eosinophils is fundamentally different between asthma ...

Peripheral eosinophilia as a potential biomarker of response and immune-related adverse events in patients with gastrointestinal tumors treated with immune checkpoint inhibitors: A single-center ...

Although both benralizumab and mepolizumab were associated with a decline in eosinophil counts, a deeper, more significant reduction was observed in the benralizumab treatment arm at all 3 time ...

In the next in our series on rare conditions that GPs might only encounter once in a career, Dr James Chambers discusses this rare syndrome and how it should be diagnosed and managed. Eosinophilic ...

Peripheral eosinophilia followed immune checkpoint treatment in six patients. Symptoms included cough, shortness of breath and dyspnea. Symptoms improved with controller therapies and rescue inhalers.

A new study has demonstrated that the peripheral eosinophil count at diagnosis can correlate with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) activity. The study, published ...

Peripheral AEC measured by cells/microL was collected within 1 week before the start of therapy. Eosinophil count was evaluated in males and females by both descriptive statistics and Chi-squared test ...

Low eosinophil/monocyte ratio was linked with a higher risk of cardiovascular death or heart failure rehospitalization. 19 A retrospective study also revealed that eosinophil percentage impacted the ...

At 4 weeks post treatment, his absolute neutrophil count returned to normal and ascites resolved. However, he experienced new abdominal pain and peripheral eosinophilia without ascites 6 months later.

Dexpramipexole inhibits the maturation and release of eosinophils in bone marrow, based on evidence from cell cultures and human biopsies, thereby lowering peripheral blood eosinophil levels.