The unfolded protein response (UPR) is a crucial signaling network that preserves endoplasmic reticulum (ER) homeostasis, impacting both health and disease. When ER stress occurs, often due to an ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

Researchers have long known that glycosaminoglycan-binding proteins (HBPs) help control vital processes like cell growth, ...

The findings illustrate the limits of even the most powerful AI tools ... Molecular Biology, the researchers evaluated whether AlphaFold, a high-profile AI system known for predicting protein ...

The MIT model predicts molecular binding affinity at newfound speed and accuracy, offering a powerful tool for commercial drug discovery.

These fundamental findings offer a novel mechanism by which rubrerythrin tubules encapsulate encapsulin to prevent oxidative stress in Pyrococcus furiosus. However, there are a few reasonable concerns ...

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation.

Scientists have identified the sex of a 2-million-year-old hominin for the first time using enamel protein analysis.

Discover how the breakthrough pill orforglipron matches injectable weight loss drugs in effectiveness while offering ...

AfCycDesign: Cyclic offset to the relative positional encoding in AlphaFold2 enables accurate structure ... of cyclic peptide monomers and binders. PinMyMetal (PMM) is an accurate tool for ...

Epilepsy is one of the most common neurological diseases in children, characterized by recurrent seizures. While genetic ...