The effect of conjugated hydrophobic polymers on the peptide secondary and tertiary structures was examined using two types of model, coiled-coil helix bundles. In particular, the integrity of the ...

The unfolded protein response (UPR) is a crucial signaling network that preserves endoplasmic reticulum (ER) homeostasis, impacting both health and disease. When ER stress occurs, often due to an ...

Most proteins are left-handed, but scientists have found an ancient molecule that works in both mirror-image forms.

Researchers have revealed the fundamental mechanisms underlying homologous recombination – one of the main DNA repair pathways in human cells.

Figure 1 shows the peptides synthesized and analyzed in this study. BKBL-20 is expected to form higher-order structures through hydrophobic face association in aqueous solution and to interact with ...

Researchers utilized recently published telomere-to-telomere genomes of humans, chimpanzees, bonobos, gorillas, and two orangutans to predict where DNA sequences might form alternative structures ...

Abstract: Short peptides composed of only a few amino acid residues are of great interest due to their biological activity and have also been shown to exhibit catalytic activity. Identifying their ...