The unfolded protein response (UPR) is a crucial signaling network that preserves endoplasmic reticulum (ER) homeostasis, impacting both health and disease. When ER stress occurs, often due to an ...

Most proteins are left-handed, but scientists have found an ancient molecule that works in both mirror-image forms.

This useful manuscript describes cryo-EM structures of archaeal proteasomes that reveal insights into how occupancy of binding pockets on the 20S protease regulates proteasome gating. The evidence ...

A molecular reinterpretation of Alice in Wonderland reveals an ancient protein with a surprising function. In a ...

The effect of conjugated hydrophobic polymers on the peptide secondary and tertiary structures was examined using two types of model, coiled-coil helix bundles. In particular, the integrity of the ...

Figure 1 shows the peptides synthesized and analyzed in this study. BKBL-20 is expected to form higher-order structures through hydrophobic face association in aqueous solution and to interact with ...

Figure 3 Secondary structures of fusion peptides in solution and bound to lipid bilayers ... The spectra were recorded at 22 ± 2°C. Contents of α-helix and orientation of the helical segments of the ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of ...

Know about the BITSAT syllabus in detail. Check the subject-wise topics, weightage, prep tips, best books on this page.

The pair really had figured out something very close to that. Working out the famous double helix structure of DNA was an achievement which led to countless advances and solved a mystery which had ...

What is the best way to drive innovative work inside organizations? Important clues hide in the stories of world-renowned creators. It turns out that ordinary scientists, marketers, programmers ...