A PCA is able to boil down a data set comprising hundreds or even thousands of dimensions (think the largest spreadsheet you’ve ever seen) into a 2D plot. (Or, depending on the type of analysis ...

CRISPR gene cuts may offer new way to chart human genome Date: February 24, 2020 Source: Johns Hopkins Medicine Summary: In search of new ways to sequence human genomes and read critical ...

NIH’s SMaHT Network will chart trillions of somatic mutations to reveal how our DNA changes over a lifetime. In a nutshell ...

Human genetic diversity and evolution rely on new mutations and exchange of DNA between chromosomes during the generation of sex cells, in a process called recombination. Recombination manifests ...

A new study maps infectious diseases across millennia and offers new insight into how human-animal interactions permanently transformed our health landscape.

The output from a DNA sequencer. ... or “reference genome,” has serious limits because it doesn’t reflect the spectrum of human diversity.

Distribution of Gnocchi scores across the genome. Credit: Nature (2023). DOI: 10.1038/s41586-023-06045-0 ...

For two decades, scientists have been comparing every person's full set of DNA they study to a template that relies mostly on genetic material from one man affectionately known as "the guy from ...