As clearly shown by the transplantation of segmental pancreatic grafts from identical twins, the autoimmune response remains many years after disease onset. 7 Thus, any β-cell replacement therapy ...

Pancreatic cancer is one of the most aggressive malignancies worldwide. Most patients are diagnosed in the middle and late stages and often develop resistance to standard chemotherapy, resulting ...

With extended follow-up and more mature data on progression-free survival (PFS) and overall survival (OS), IBI343 has demonstrated promising therapeutic efficacy in patients with CLDN18.2-positive ...

Insulin is a hormone produced by the pancreas in response to high blood glucose levels. It plays a crucial role in the regulation of glucose metabolism in the body (Saltiel and Kahn, 2001). In ...

CHICAGO and FORT WORTH, Texas, May 22, 2025 (GLOBE NEWSWIRE) -- Actuate Therapeutics, Inc. (NASDAQ: ACTU) (“Actuate” or the “Company”), a clinical-stage ...

Phase 2 (Actuate-1801 Part 3B) trial topline results meet primary endpoint of improved survival in previously untreated patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) Oral ...