Osteomalacia is a weakening of the bones. When not treated, it can lead to serious health complications, such as fractures and severe deformity. Here, we look at causes, symptoms, diagnosis ...

But while osteomalacia is a problem with bones not hardening, osteoporosis is the weakening of the bone. Causes Your bones rely on certain minerals to grow strong and stay solid.

The causes of osteomalacia can usually be determined readily. They may be classified into two groups: those in which ingested calcium or phosphorus is not absorbed from the gastrointestinal tract; ...

FGF-23–dependent causes of hypophosphatemia include tumor-induced osteomalacia (a rare paraneoplastic syndrome in which a tumor secretes FGF-23) and X-linked, autosomal-dominant, and autosomal ...

“The pathophysiology of tumor-induced osteomalacia, driven by increased paraneoplastic production of FGF23, is similar to that of XLH, where renal tubular phosphate wasting occurs due to excess ...

Medically reviewed by Jonathan B. Jassey, DOMedically reviewed by Jonathan B. Jassey, DO Rickets is a medical condition that ...

Vitamin D deficiency: Long term deficiency causes pain felt at night known as osteomalacia VITAMIN D deficiency largely affects a person's bones and muscles.

Discussion. Hypophosphatemia is the primary biochemical abnormality in patients with oncogenic osteomalacia. Patients invariably have decreased 1,25 (OH) 2 D3 serum concentrations as a consequence ...