Molecular mechanisms of birth ... This means that a prerequisite for error-free segregation in human oocytes is that meiotic cohesion established in oocytes during fetal development must ...

Oocyte maturation and follicular development are fundamental processes that underpin female fertility. ... ovulatory follicles through tightly regulated cellular and molecular mechanisms.

Females are born with a finite number of eggs that are steadily depleted throughout their lifetime. This reserve of eggs is selected from a much larger pool of millions of precursor cells; there is a ...

Scientists have characterized a mechanism that allows for asymmetrical cell division during meiosis in oocytes. By tracking chromosome movement in live mouse oocytes, they have discovered that ...

Moreover, the development of future oocytes produces a 'bottleneck' that reduces the possibility of heteroplasmy. On rare occasions, these processes can fail, producing heteroplasmic individuals." ...

Dartmouth researchers studying cell division in fruit flies have discovered a pathway that may improve understanding of molecular mistakes that cause older women to have babies with Down syndrome.

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the ...

The Stowers Institute's Rong Li Lab has characterized a mechanism that allows for asymmetrical cell division during meiosis in oocytes. By tracking chromosome movement in live mouse oocytes, the ...