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This addition involves formation of a covalent bond called the ‘phosphodiester bond’. This is formed between the 5’-phosphate group of one nucleotide and the 3’-OH group of another ...
This, of course, poses quite a conundrum, as many believe single-electron chemical bonds can’t exist. That’s because all of the current known covalent bonds—where atoms connect by sharing ...
Chemistry students the world over are familiar with covalent bonds and hydrogen bonds. Now a study has revealed a strange variety of bond that acts like a hybrid of the two. Its properties raise ...
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A covalent bond links lysine and cysteine in proteins together under oxidizing conditions, stabilizing themThe folded shape is maintained by a series of forces and bonds, including certain types of covalent bonds where atoms in different amino acids in the protein are physically joined together.
Synthetic routes that involve non-covalent assembly techniques are ... same way that DNA helices are held together by hydrogen bonds in nucleotide base pairs — and the rigid sections point ...
Although drugs that make covalent bonds with their biological targets are as old as the pharmaceutical industry, intentionally designing molecules that make such bonds is relatively new.
As any chemistry student knows, molecular bonds, or covalent bond structures, are typically represented in science class with a stick-like nomenclature. But as the work of Felix Fischer ...
Prior to 2000, many drugs that formed a covalent bond with targets did so non-selectively, which often led to undesired side effects when compared to non-covalent drugs. This led to the belief that ...
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