Figure 3: Activation pathway in plasmacytoid dendritic cells responding to nucleic acids. A recent study however challenges the concept of self versus non-self discrimination based on the presence ...

Innovative delivery techniques, including high-tech nanoparticles and electroporationdevices, may convey more gene therapies into the clinic.

This research sheds light on the complex interactions between nucleic acid sensors and enzymes in immune cells and paves the way for more precise immune therapies.

A researcher in Purdue University’s College of Science is developing a patent-pending platform technology that mimics the dual-layer structure of viruses to deliver nucleic acid (NA)-based therapies ...

Resolve Therapeutics, a leader in the emerging field of cell-free nucleic acid therapeutics, today announced a collaboration ...

Urinary cell-free DNA (cfDNA) is a valuable source of nucleic acids for developing non-invasive tests. For example, stabilized cfDNA is amenable to quantitative polymerase chain reaction (qPCR) and ...

Development of an Elastin-like Polypeptide-Based Nucleic Acid Delivery System Targeted to EGFR+ Bladder Cancer Cells Using a Layer-by-Layer Approach. Biomacromolecules , 2024; DOI: 10.1021/acs ...