Inspired by the way viruses attach to cells, EPFL scientists have developed a method for engineering ultra-selective aptamers ...

The model can predict proteins that haven’t been “structurally characterized” before, while at the same time simulating how proteins and nucleic acids interact with other molecules — a ...

Computer simulations help materials scientists and biochemists study the motion of macromolecules, advancing the development ...

Nucleic Acids 2017, DOI: 10.1016/j.omtn ... That makes them active in animal models at doses as low as 10 ng/kg, many orders of magnitude lower than existing antisense oligonucleotides.

Scientists have may have successfully reproduced what's believed to be the first thing that ever lived on Planet ...

Telesis Bio has announced a licensing agreement with Regeneron, enabling the latter to deploy the Gibson SOLA platform at R&D ...

The laboratories at Rockefeller University continue to be a model for interdisciplinary research and the training ground for tomorrow's scientists. The American Chemical Society dedicated nucleic acid ...

Comparing literature-based cell-free miRNA panels to whole genome miRNA screening for cancer detection. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does not ...

A researcher is developing a patent-pending platform technology called LENN that mimics the dual-layer structure of viruses to deliver nucleic acid (NA)-based therapies to targeted cancer cells.

Aberrant nucleic acid structures are key to endogenous repair ... the systemic in vivo application of PNAs to enable gene editing in preclinical mouse models. In a β-thalassemia model, treated animals ...