Computer simulations help materials scientists and biochemists study the motion of macromolecules, advancing the development ...

The model can predict proteins that haven’t been “structurally characterized” before, while at the same time simulating how proteins and nucleic acids interact with other molecules — a ...

Scientists have identified sequences in great apes' DNA capable of forming unconventional structures called non-B DNA. These ...

Nucleic Acids 2017, DOI: 10.1016/j.omtn ... That makes them active in animal models at doses as low as 10 ng/kg, many orders of magnitude lower than existing antisense oligonucleotides.

Telesis Bio has announced a licensing agreement with Regeneron, enabling the latter to deploy the Gibson SOLA platform at R&D ...

The laboratories at Rockefeller University continue to be a model for interdisciplinary research and the training ground for tomorrow's scientists. The American Chemical Society dedicated nucleic acid ...

The flow of genetic information underpins all of biology and relies heavily on nucleic acids. Our research delves into how genetic ... We employ a range of model organisms in our research, from ...

Aberrant nucleic acid structures are key to endogenous repair ... the systemic in vivo application of PNAs to enable gene editing in preclinical mouse models. In a β-thalassemia model, treated animals ...

A researcher is developing a patent-pending platform technology called LENN that mimics the dual-layer structure of viruses to deliver nucleic acid (NA)-based therapies to targeted cancer cells.