A 52-year-old man presented to our orthopedic clinic with an 8-month history of a right distal forearm mass accompanied by ...

Pro-905, a Novel Purine Antimetabolite, Combines with Glutamine Amidotransferase Inhibition to Suppress Growth of Malignant Peripheral Nerve Sheath Tumor. Molecular Cancer Therapeutics , 2023; 22 ...

DEAR DR. ROACH: For several months, I’ve been suffering with severe lower-back pain while standing. It radiates down my leg, into my buttocks. Several weeks of physical therapy was not helpful ...

The focus of this month’s blog post is a discussion of malignant peripheral nerve sheath tumors (MPNSTs), which represent one of the few potentially life-threatening complications of neurofibromatosis ...

Tumors of these cells are called schwannomas. Often, they are found in the nerve connected to the ear, affecting the sense of balance. They also arise in the nerves leaving the spine.

A combination of two cancer drugs could be effective against malignant peripheral nerve sheath tumors (MPNSTs) - soft tissue tumors that are stubbornly resistant to chemotherapy and radiation ...

H3K27me3 Immunohistochemical Expression in Malignant Peripheral Nerve Sheath Tumors. The results of the immunohistochemical analysis are summarized in Tables 1 and 2.Seventy-two percent (n=88) of ...

Spindle cell sarcomas often present the surgical pathologist with a considerable diagnostic challenge. Malignant peripheral nerve sheath tumor, leiomyosarcoma, fibrosarcoma, and monophasic ...

Cortes-Ciriano, I., et al. (2023) Genomic patterns of malignant peripheral nerve sheath tumor (MPNST) evolution correlate with clinical outcome and are detectable in cell-free DNA. Cancer ...

DEAR DR. ROACH: For several months, I’ve been suffering with severe lower-back pain while standing. It radiates down, into my buttocks. Several weeks of physical therapy was not helpful, and I ...

Genomic profiling of mostly untreatable and deadly nerve sheath tumors led scientists to test a possible therapeutic strategy that inhibited tumor growth in lab tests on human tumor cells and ...