In this study, we investigated the interplay between cigarette smoke, DNA damage and repair, focusing on the Nucleotide Excision Repair (NER) protein ...

Efficient DNA repair mechanisms have evolved to ... xeroderma pigmentosum complementing protein B; NER, nucleotide excision repair; pol η, polymerase η; SSB, single-strand break; TCR ...

An outline of the nucleotide excision repair pathway, which includes global genomic repair (1B) and transcription-coupled repair (1A). The damaged base in the DNA is indicated by a green star.

A powerful new discovery reveals that Nup98 a protein once thought to only ferry molecules through the nucleus plays a vital ...

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A ...

When DNA breaks inside the cell, it can spell disaster, especially if the damage occurs in areas of the genome that are ...

However, another cellular polymerase can substitute for β-pol to incorporate a single nucleotide residue in the repair of MMS-induced DNA damage. It remains to be determined whether repair of DNA ...

Scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have made one of the most ...

The CRISPR gene editing technology has transformed the research lab, and this powerful tool is now making its way into the clinic... | Cell And Molecular Biology ...

The DNA damage response is a network of cellular pathways that sense, signal and repair DNA lesions. Surveillance proteins that monitor DNA integrity can activate cell cycle checkpoints and DNA ...