The application of CAR-T cell therapy against solid tumors is often hindered by the dense and rigid tumor extracellular ...

A multi-pronged treatment for metastatic cancer, it contains two agents: Interleukin-2 (IL-2) and an inhibitor of tissue growth factor (TGF beta). IL -2 amplifies the body’s immune system, while the ...

The efficacy of CAR-T cells in ablating solid tumors is significantly impeded by the densely packed tumor extracellular matrix (ECM). This physical ...

The nanogel compound, for which FIU has received a patent in the United States, could have a worldwide impact. Because it is non-toxic, organic and inexpensive to produce, it could offer a safe and ...

An immunotherapy drug delivery system created at Yale that can carry multiple drugs inside a tiny particle is heading toward its first phase of clinical trials for a possible new treatment for cancer.

A DNA-based nanogel for targeted chemotherapy Date: November 18, 2020 Source: American Chemical Society Summary: Current chemotherapy regimens slow cancer progression and save lives, but these ...

The researchers wanted to see whether they could design a DNA nanogel that would specifically be degraded in cancer cells by FEN1. To make DNA nanogels, the researchers used special DNA structures ...

The first step in many cancer treatments is to surgically remove the tumor, however this often isn’t enough. As long as a few cancer cells remain the tumors often grow back, but a new innovative ...

A more effective treatment option. The researchers discovered that nanogel technology can carry more than enough gentamicin to be effective—about 36% more gentamicin inside cells compared to ...

Leukemia Cell Hitchhiking Hypoxia Responsive Nanogel for Improved Immunotherapy of Acute Myeloid Leukemia. Journal: Advanced Functional Materials Published: 2024-09-15 ...

Current chemotherapy regimens slow cancer progression and save lives, but these powerful drugs affect both healthy and cancerous cells. Now, researchers reporting in ACS' Nano Letters have ...