The adaptor proteins MyD88 and the associated protein IL-1R ... IL-33 stimulation may include phosphorylation of extracellular signal-regulated kinase (ERK) 1/2, p38 MAPK, JNKs and activation ...

Photodynamic therapy (PDT) resistance limits treatment efficacy in oral leukoplakia (OLK). This study identifies p-NRF2 as a ...

Scientists discovered a novel signaling pathway in liver cells, leading to a treatment for fibrosis. A healthy liver filters all the blood in your body, breaks down toxins and digests fats.

Identifying proteomic signatures of insulin resistance in fasting muscle offers insights for personalized type 2 diabetes ...

Pathway-focused metabolite ratio-based analysis of 49 tumor and 8 normal epithelial cell lines grown in their respective ...

Pro-inflammatory signaling molecules in MS cause problems with the growth and development of myelin-making cells in the brain ...

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways ...

where calcium imbalance and impaired synaptic signaling are key features. This newly identified GPR158–PLCXD2 axis offers insight into how synaptic structure and receptor content are regulated ...

Inflammation plays a crucial role in the development of various diseases, including cancer, allergic diseases, such as asthma, and cardiovascular diseases, such as atherosclerosis and heart failure.

Unlike PHT1 transporters, which are directly involved in Pi uptake, NF-YC TFs play a central role in orchestrating the expression of multiple downstream genes, including P transporters and genes ...

Center for the Study of Systems Biology Georgia Institute of Technology 950 Atlantic Dr NW Atlanta, Georgia 30332, United States ...