A new study from the Max Planck Institute for Evolutionary Biology has uncovered how the MN1 gene evolved to shape both the ...

Scientists discovered a new way to protect memory in Alzheimer's by targeting the blood-brain barrier instead of amyloid ...

Infectious diseases such as gonorrhea or chlamydia are often overlooked factors that affect fertility in men. Accumulating evidence suggests that a common single-celled parasite called Toxoplasma ...

Genprex, Inc. ("Genprex" or the "Company") , a clinical-stage gene therapy company focused on developing life-changing therapies for patients with cancer and diabetes, announced that its research ...

Nitrous oxide, a commonly used analgesic gas, temporarily improved the opening of the blood-brain barrier (BBB) to allow gene therapy delivery in mouse models using focused ultrasound (FUS), UT ...

The work revealed surprising principles of brain organization, including new inhibitory cell behaviors and ... the brain wiring in a healthy mouse to the brain wiring in a model of disease.” ...

These included microglia, border-associated macrophages, oligodendrocytes (which help insulate nerve fibers), ependymal cells (which help ... they do not develop age-related brain diseases in the same ...

The scientific teams are building a new model of a different autoimmune condition affecting brain borders ... to mouse brains, marmoset and human brains have a higher ratio of white matter (the “wires ...

At just 125 cells per mouse, the dural Treg population was tiny but unmistakable ... They confirmed that the blood-brain border remained largely intact, suggesting the cells did not wander in from the ...

Tregs dwelling at the brain border act as gatekeepers The ... was reminiscent of the damage and immune-cell activity seen in human and mouse brains with Alzheimer's disease.

known as brain support cells, that underwent significant gene expression changes with age. Those strongly affected included microglia and border-associated macrophages, oligodendrocytes ...

New study reveals how lingering spike protein in the brain's borders could explain long-term ... In a recent study published in the journal Cell Host & Microbe, researchers investigated the ...