Patients with type 2 diabetes mellitus are at a higher risk of developing heart failure compared with the healthy population. In recent landmark clinical trials, sodium-glucose co-transporter 2 (SGLT2 ...

The cellular composition and underlying spatiotemporal transformation processes of subchondral bone in osteoarthritis (OA) remain unknown. Herein, various cell subsets from tibial plateau of patients ...

Morphine has been used to treat dyspnea for centuries, although the exact mechanism of action remains unclear. Opioids may diminish the chemoreceptor response to hypercapnia and hypoxia, ...