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The Swiss drugmaker says the safety and efficacy of zosurabalpin will be investigated in a study involving 400 patients with ...
Debiopharm initially received funding from CARB-X in 2017 for pre-clinical development of Debio1453, which inhibits an ...
Since the discovery of penicillin nearly a century ago, antimicrobial resistance (AMR) has become a stealthy, pervasive enemy ...
Obesity can have a distinct impact on the absorption, effectiveness and excretion of antibiotics, medications that have been ...
Debio 1453 is a potent inhibitor of the essential fatty acid synthesis enzyme FabI found in N. gonorrhoeae and a few other bacterial species. It was shown to rapidly trigger bactericidal activity in ...
Using electron microscopy, researchers illustrate FusB's role in antibiotic resistance, providing a molecular-level ...
Researchers describe a fundamental mechanism of antibiotic resistance. What happens in a bacterium that is resistant to the antibiotic fusidic acid? With a stop-motion movie at the atomic level, they ...
Fermenta Biotech Limited, a leading player in the field of nutritional ingredients and food fortification, is pleased to ...
Insert length between 800 and 3000 bp. ‡‡ One clone was resistant to all three antibiotic classes in a secondary screen. The generic term 'antibiotic' is used to denote any class of organic ...
Scientists uncovered how the resistance protein FusB deflects fusidic acid in bacteria, using atomic-level imaging to reveal a crowbar-like resistance mechanism.
The star of the story is saarvienin A, a brand-new glycopeptide antibiotic produced by an unusual strain of Amycolatopsis, a ...