Tocilizumab alone and in combination with methotrexate outperformed the latter drug in patients who did not adequately ...

Doctors may prescribe either medication as an alternative to methotrexate. Taking DMARDs to treat PsA is also an off-label use. DMARDs can take several weeks or months to have a noticeable effect.

Methotrexate is a cheap ... Yet few are aware that it is used off-label to end ectopic pregnancies, or that it could be restricted by doctors or pharmacists even in states like Virginia that ...

The FDA and Health Canada "should also consider issuing warning labels to inform prescribers of the study's findings," the researchers wrote. Methotrexate is commonly prescribed for rheumatoid ...

But it can also be used off-label in very high doses to treat a ... the law classifies methotrexate as a drug that can induce abortion and groups it with the other two, meaning there can be ...

Patients who take methotrexate for a variety of immune-mediated ... they reported results from a randomized, open-label, superiority trial that suggested pausing the drug improved immunogenicity ...

Now new research, published at the ATS 2025 International Conference and in the American Journal of Respiratory and Critical Care Medicine, finds that methotrexate provides a comparable alternative.

A recent open-label, uncontrolled trial found that adding tacrolimus to the regimen of patients with a suboptimal response to methotrexate could be beneficial. After 6 months' treatment ...