Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume ...

A UCO team has applied the genome editing technique, which garnered a Nobel Prize in Chemistry in 2020, to unravel the ...

Adenylosuccinate lyase deficiency (ADSLD) is a rare genetic disorder that affects purine metabolism, leading to various neurodevelopmental issues. Purines are essential building blocks for DNA and ...

Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume. They also have a ...

Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume ...

Recent research has focused on understanding the roles of different enzymes involved in nucleotide metabolism, particularly in the context of purine and pyrimidine nucleotide biosynthesis and ...

Learn how consuming this yellow fruit can help lower uric acid levels and cleanse your stomach. Get expert tips on when and how to eat it for maximum benefits.

Conclusion Oxidative stress, especially through purine metabolism pathway, is a major metabolic event during reperfusion and may contribute to the ischaemia reperfusion injury of lung grafts. Data are ...

RNA-seq and MS analyses indicated that L-arginine switched glycolysis to oxidative phosphorylation in inflammatory osteoclasts leading to increased ATP production, purine metabolism and elevated ...

facilitating immunogenicity induced by increased mutability and genomic instability via disrupting the purine and pyrimidine pool, and releasing nucleoside analogs via microbes to modulate immunity.

XORTX is working to advance its clinical development stage products that target aberrant purine metabolism and xanthine oxidase to decrease or inhibit production of uric acid. At XORTX, we are ...