As 'Grey's Anatomy' delivers explosive Season 21 finale cliffhanger, showrunner talks lives in danger, couples at crossroads, new cast addition & more ...

Simone is someone else who is going to have a complicated situation when you return for Season 22. That also felt like a throwback to Meredith and Derek, when her hookup showed up at work.

Actor Patrick Dempsey departed Grey's Anatomy years ago, but some are unclear about which episode his character Derek died in and why he left.

But Derek, I love you… in a really, really big, pretend to like your taste in music, let you eat the last piece of cheesecake, hold a radio over my head outside your window, unfortunate way that makes ...

Chances are, you’ll remember the moment Meredith Grey (Ellen Pompeo) realizes her one-night stand Derek Shepherd (Patrick Dempsey) is her boss, when Richard Webber (James Pickens Jr.) delivers ...

“Your choice, it’s simple,” Meredith tells Derek during the season 2 episode, which first aired in 2005. “Her, or me." Her speech concludes with the now-iconic line, “So pick me. Choose me.

Pick Us, Choose Us, Love Us! For exclusive news and updates, subscribe to our Grey's Anatomy Newsletter: Meredith Grey is the original “pick me girl,” but it’s not a title Ellen Pompeo ever ...

Meredith Gaudreau shared an emotional note to her late husband, Johnny Gaudreau, two months after his death. “John, we love you so much,” Meredith wrote via Instagram on Tuesday, October 29 ...

There is a lot of Grey's Anatomy to go around. Have you ever wondered what storyline was the best from each season? We have!

While it originally played during one of Meredith and Derek's first dates, it returns in Sandra Oh's last appearance Cristina Yang in Season 10, with she and Meredith dancing it out one last time.

Meredith feared the worst, and she was almost right, for Derek did end up kissing Renee - although it's possible this kiss opened his eyes and drove away any confusion he might have had.