Mefloquine is a synthetic compound but its chemical structure is based on one of the first malaria drugs, quinine, that comes from the bark of South America’s Cinchona tree. It’s not certain ...

The structural information from (+)-mefloquine bound to the ribosome demonstrates that three key elements of the (+)-mefloquine structure (quinoline, alcohol and piperidine) all contribute ...

New systematic reviews have investigated the safety of mefloquine (Lariam) for preventing malaria in travelers. Researchers from LSTM Cochrane Infectious Diseases Group publish two systematic ...

falciparum malaria. Patients underwent randomization for treatment with a fixed-dose combination of 180 mg of pyronaridine and 60 mg of artesunate or with 250 mg of mefloquine plus 100 mg of ...